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    <Identifier>mibe000120</Identifier>
    <IdentifierDoi>10.3205/mibe000120</IdentifierDoi>
    <IdentifierUrn>urn:nbn:de:0183-mibe0001201</IdentifierUrn>
    <ArticleType>Research Article</ArticleType>
    <TitleGroup>
      <Title language="en">The 3LGM<Superscript>2</Superscript>-tool to support information management in health care</Title>
      <TitleTranslated language="de">Der 3LGM<Superscript>2</Superscript>-Baukasten zur Unterst&#252;tzung des Informationsmanagements im Gesundheitswesen</TitleTranslated>
    </TitleGroup>
    <CreatorList>
      <Creator>
        <PersonNames>
          <Lastname>Winter</Lastname>
          <LastnameHeading>Winter</LastnameHeading>
          <Firstname>Alfred</Firstname>
          <Initials>A</Initials>
        </PersonNames>
        <Address>Institute for Medical Informatics, Statistics und Epidemiology, Leipzig University, Leipzig, Germany, Phone: &#43;49-(0)-341-9716107, Fax: &#43;49-(0)-341-9716109<Affiliation>Institute for Medical Informatics, Statistics und Epidemiology, Leipzig University, Leipzig, Germany</Affiliation></Address>
        <Email>alfred.winter&#64;imise.uni-leipzig.de</Email>
        <Creatorrole corresponding="yes" presenting="no">author</Creatorrole>
      </Creator>
    </CreatorList>
    <PublisherList>
      <Publisher>
        <Corporation>
          <Corporatename>German Medical Science GMS Publishing House</Corporatename>
        </Corporation>
        <Address>D&#252;sseldorf</Address>
      </Publisher>
    </PublisherList>
    <SubjectGroup>
      <SubjectheadingDDB>610</SubjectheadingDDB>
      <Keyword language="en">3LGM&#178;</Keyword>
      <Keyword language="en">hospital information systems</Keyword>
      <Keyword language="en">transinstitutional health information systems</Keyword>
      <Keyword language="en">information management</Keyword>
      <Keyword language="de">3LGM&#178;</Keyword>
      <Keyword language="de">Krankenhausinformationssysteme</Keyword>
      <Keyword language="de">transinstitutionelle Informationssysteme des Gesundheitswesens</Keyword>
      <Keyword language="de">Informationsmanagement</Keyword>
    </SubjectGroup>
    <DatePublishedList>
      
    <DatePublished>20110622</DatePublished></DatePublishedList>
    <Language>engl</Language>
    <SourceGroup>
      <Journal>
        <ISSN>1860-9171</ISSN>
        <Volume>7</Volume>
        <Issue>2</Issue>
        <JournalTitle>GMS Medizinische Informatik, Biometrie und Epidemiologie</JournalTitle>
        <JournalTitleAbbr>GMS Med Inform Biom Epidemiol</JournalTitleAbbr>
      </Journal>
    </SourceGroup>
    <ArticleNo>06</ArticleNo>
  </MetaData>
  <OrigData>
    <Abstract language="de" linked="yes"><Pgraph>Sowohl Krankenhausinformationssysteme als auch transinstitutionelle Informationssysteme sind &#228;hnlich wie Geb&#228;ude(komplexe) aus meist heterogenen Bausteinen und Komponenten zusammengesetzt. &#196;hnlich wie ein Architekt, ben&#246;tigt ein Informationsmanager eine Beschreibung, d.h. ein Modell der Informationssystem-Architektur. Mit dem Metamodell 3LGM<Superscript>2</Superscript> k&#246;nnen solche Architekturen beschrieben bzw. modelliert werden. Hierzu werden Konzepte auf drei Ebenen verwendet. Passend zu 3LGM<Superscript>2</Superscript> ist eine Modellierungssoftware verf&#252;gbar, die mit ihren Analysemethoden das strategische, taktische und operative Informationsmanagement unterst&#252;tzen kann. </Pgraph></Abstract>
    <Abstract language="en" linked="yes"><Pgraph>Hospital information systems (HIS) as well as transinstitutional health information systems (tHIS) are constructed like a (complex of) building(s) out of different and probably heterogeneous bricks and components. Like an architect the information manager needs a description or model for the information system&#8217;s architecture respectively the enterprise architecture. 3LGM<Superscript>2</Superscript> as a meta model has been designed to describe information systems (IS) by concepts on three layers. The meta model has been supplemented by the 3LGM<Superscript>2</Superscript> tool. It enables information managers to graphically design even complex IS and provides means for analyzing information system&#8217;s quality and thus supports strategic, tactical and operational information management. </Pgraph></Abstract>
    <TextBlock linked="yes" name="1 Introduction">
      <MainHeadline>1 Introduction</MainHeadline><Pgraph>A mayor driving force for healthcare is still the trend towards a better continuity of care <TextLink reference="1"></TextLink>. Health care professionals <TextGroup><PlainText>in different departments of a hospital but</PlainText></TextGroup> moreover in a region &#8211; and in many cases even worldwide &#8211; have to cooperate in order to achieve health for the patient <TextLink reference="2"></TextLink>.</Pgraph><Pgraph>Cooperation needs an adequate system for communicating and processing of information, i.e. an information system, which is that socio-technical subsystem of a (set of) health care institution(s), which presents information at the right time, in the right place to the right people <TextLink reference="3"></TextLink>, <TextLink reference="4"></TextLink>. </Pgraph><Pgraph>Hospital information systems (HIS) as well as transinstitutional health information systems (tHIS) <TextLink reference="5"></TextLink> (consisting of different institutional information systems) are constructed like a (complex of) building(s) out of different and probably heterogeneous bricks and components. Thus cooperation depends especially on the availability of adequate communication links between the institutional information systems and their components. Besides technical problems of communication links there are a lot of complex problems of connecting heterogeneous software components of different vendors and with different database schemata to be solved. Like an architect the information manager needs a blueprint or model for the information system&#8217;s architecture respectively the enterprise architecture <TextLink reference="6"></TextLink>, <TextLink reference="7"></TextLink>. </Pgraph><Pgraph>The paper deals with the question of how the three layer graph based meta model (3LGM<Superscript>2</Superscript>) <TextLink reference="8"></TextLink> and the 3LGM<Superscript>2</Superscript> tool  <TextLink reference="9"></TextLink> can be used for describing and modeling HIS and tHIS and how 3LGM<Superscript>2</Superscript> can support information managers in <TextGroup><PlainText>their planning, directing and monitoring activities.</PlainText></TextGroup> Therefore our concept of information management will be explained first. The second section will introduce the main features of 3LGM<Superscript>2</Superscript> and the 3LGM<Superscript>2</Superscript> tool. Finally the tool&#8217;s analyzing features to support information management will be illustrated.</Pgraph></TextBlock>
    <TextBlock linked="yes" name="2 Information management">
      <MainHeadline>2 Information management</MainHeadline><Pgraph>According to <TextLink reference="3"></TextLink> information management in hospitals is the sum of all management activities in a hospital that transpose the potential contribution of information processing to fulfill the strategic hospital goals into hospital&#8217;s success. </Pgraph><Pgraph>Therefore, it manages the maintenance and operation of the hospital  information system. </Pgraph><Pgraph>The question of information management focuses on the issue, whether the performance of the information system can be enhanced, for example by using adequate computer-supported information processing tools. Accordingly, information management engages in the following objects <TextLink reference="7"></TextLink>: enterprise functions and entity types, i.e. types of  information, used by these functions, application components, data processing systems like computer-supported and non-computer-supported information and communication tools.</Pgraph><Pgraph>The general tasks of management are planning, directing, and monitoring. For information management in hospitals this means <Mark2>planning</Mark2> the hospital information system, respectively its architecture, <Mark2>directing</Mark2> its establishment and its operation, and <Mark2>monitoring</Mark2> its development and operation with respect to the planned objectives.</Pgraph><Pgraph>Information management in hospitals is a complex task. In order to reduce complexity, we distinguish strategic, tactical, and operational information management. This is essential, because each of these information management levels views hospital information systems from different perspectives, and therefore uses other methods and tools. </Pgraph><Pgraph>In summary, activities of information management can be classified by a three dimensional classification as depicted in Figure 1 <ImgLink imgNo="1" imgType="figure"/>.</Pgraph></TextBlock>
    <TextBlock linked="yes" name="3 3LGM&#178;">
      <MainHeadline>3 3LGM&#178;</MainHeadline><SubHeadline>3.1 The Meta Model 3LGM<Superscript>2</Superscript></SubHeadline><Pgraph>The three layer graph based meta model (3LGM<Superscript>2</Superscript>) has been designed to describe information systems by concepts on three layers <TextLink reference="8"></TextLink>. </Pgraph><Pgraph>The domain layer of 3LGM<Superscript>2</Superscript> describes a hospital independently of its implementation by its enterprise functions. Enterprise functions describe what has to be done in the institution. They need information of a certain type about physical or virtual things of the hospital. These types of information are represented as entity types. The access of an enterprise function to an entity type can be in a using or an updating manner</Pgraph><Pgraph>The <Mark2>logical tool layer</Mark2> concentrates on <Mark2>application components</Mark2> supporting enterprise functions. Application components are responsible for the processing, storage and transportation of data representing entity types. Application components may have a local <Mark2>database</Mark2> to store data. <Mark2>Component interfaces</Mark2> ensure the communication among application components. A component interface can receive or send messages of a certain message type. A message type transports (a) certain entity type(s). For the communication among application components <Mark2>communication links</Mark2> can be defined as relations between two communication interfaces, one being the sender of a message, the other one being the receiver.</Pgraph><Pgraph>The <Mark2>physical tool layer</Mark2> consists of physical data processing systems (like personal computers, servers, switches, routers, etc), which are physically connected via data transmission connections (e.g. data wires). </Pgraph><Pgraph>Between concepts of the different layers there exist so-called interlayer relationships, which enable to describe the dependencies between model elements belonging to different layers. In this paper, the following interlayer relationships are of special interest:</Pgraph><Pgraph><UnorderedList><ListItem level="1">An enterprise function is supported by a set of application components. </ListItem><ListItem level="1">An Entity type can logically be represented by a dataset type or a message type to describe how it is stored and communicated. Dataset types describe what information is stored in a database; message types describe what information is transported by a communication link between two application components. </ListItem></UnorderedList></Pgraph><SubHeadline>3.2 The 3LGM<Superscript>2</Superscript> tool</SubHeadline><Pgraph>The meta model has been supplemented by the 3LGM<Superscript>2</Superscript> tool <TextLink reference="9"></TextLink>. It enables information managers to graphically design even complex HIS and assists information managers similarly to computer aided design tools (CAD) supporting architects. The tool provides means for analyzing a HIS or a tHIS model and thus for assessing tHIS&#8217;s quality. </Pgraph><Pgraph>The 3LGM<Superscript>2</Superscript> tool is a software product designed to create information system models on the basis of 3LGM<Superscript>2</Superscript> (Figure 2 <ImgLink imgNo="2" imgType="figure"/>). On the modeling canvas, which dominates the main window of the tool, an information system can be modeled and displayed on three layers. A model diagram is a graph; i.e. consists of nodes and edges. There are different node types corresponding to the element classes defined in the 3LGM<Superscript>2</Superscript> as mentioned before. </Pgraph><Pgraph><UnorderedList><ListItem level="1">On the top layer &#8211; the <Mark2>domain layer</Mark2> &#8211; the hospital&#8217;s enterprise functions and entity types used by these functions are displayed.</ListItem><ListItem level="1">The middle layer &#8211; the <Mark2>logical tool layer</Mark2> &#8211; contains application components, database systems, document collections, component interfaces and communication links between them. Application components support functions and store data about entity types in database systems. These relations are modeled explicitly by linking elements from the logical tool layer to elements of the domain layer and can be displayed as interlayer relationships like in Figure 2 <ImgLink imgNo="2" imgType="figure"/>.</ListItem><ListItem level="1">The bottom layer &#8211; the <Mark2>physical tool layer</Mark2> &#8211; contains the physical tools: record shelves, computers, network components and even personnel, i.e. &#8216;touchable&#8217; components of the information systems. Physical data processing systems are the basis for application components. Similar to the relations between the domain layer and the logical tool layer, relations between the latter and the physical tool layer are modeled explicitly by linking model elements.</ListItem></UnorderedList></Pgraph><Pgraph>Each of the element classes function, entity type, application component, database system, document collection, component interface, and physical data processing component is visualized in the model diagram and has a default geometric shape and a default background color. </Pgraph><Pgraph>The three different layers can be viewed and edited separately but can also be combined in a multi-layer view as shown in Figure 2 <ImgLink imgNo="2" imgType="figure"/>. A lot of analysis functions are provided. Thus users can find e.g. those enterprise functions which are supported by a selected server. Additionally quality indicators like data redundancy are calculated.</Pgraph></TextBlock>
    <TextBlock linked="yes" name="4 The 3LGM&#178; for information management">
      <MainHeadline>4 The 3LGM&#178; for information management</MainHeadline><SubHeadline>4.1 The 3LGM<Superscript>2</Superscript> for strategic information management</SubHeadline><Pgraph>Strategic information management deals with the hospital&#8217;s information processing as a whole. It depends strictly on the hospital&#8217;s business strategy and strategic goals and has to translate these into a well fitting information system. </Pgraph><Pgraph>The result of strategic information management <Mark2>planning</Mark2> activities is a strategic information management plan <TextLink reference="10"></TextLink>. The plan describes the direction and strategy of information management and gives directives for the construction and development of the hospital information system by describing its intended architecture. It includes a description of the current state of the information system and a description of its planned state. </Pgraph><Pgraph>Using the 3LGM<Superscript>2</Superscript> tool continuously can provide information management with a documentation of the managed information system as a whole which might be up-to-date. The tool&#8217;s means for generating reports as well as graphical illustrations can easily be used for describing the current state of the information system within a strategic plan. Modifying the model according to the &#8220;directives for the construction and development of the hospital information system&#8221; (as said before) will help to describe the intended architecture. Reportedly 3LGM<Superscript>2</Superscript> has been used in this context in some German academic medical centers <TextLink reference="11"></TextLink>, <TextLink reference="12"></TextLink>, <TextLink reference="13"></TextLink> and especially in Leipzig <TextLink reference="14"></TextLink>.</Pgraph><Pgraph>The description and the assessment of the current state is the basis for identifying those functions of the hospital that are well supported, and those functions that are not (yet) well supported. However, describing and modeling the information system from scratch is often found rather labor costly. Reference models for a HIS may be very useful here, as they can be used as model patterns. One further advantage of reference models is that they help to standardize HIS terminology between various institutions <TextLink reference="15"></TextLink>. A reference model for the domain layer of a Hospital Information System for describing the enterprise functions and entity types has been presented in <TextLink reference="16"></TextLink>. </Pgraph><Pgraph>Especially in the setting of a transinstitutional health information system (tHIS) a proper and comparable description of the institutional information systems being part of the tHIS and their relationships is essential for strategic planning. We applied the 3LGM<Superscript>2</Superscript> tool to construct a 3LGM<Superscript>2</Superscript> model of the tHIS of Saxony, which is federal state of Germany <TextLink reference="17"></TextLink>. The tHIS of Saxony has been further developed by the SAXTELEMED project, funded by the Saxonian ministry of social affairs <TextLink reference="18"></TextLink>. The project focused mainly on the exchange of radiological images and intended to improve integration of ambulatory and inpatient care. </Pgraph><Pgraph>Figure 3 <ImgLink imgNo="3" imgType="figure"/> gives an overview of the model (SAX-tHIS model) at the logical tool layer. At a low level of granularity it shows the hospital information systems and the information systems of practitioners involved as application components. The 3LGM<Superscript>2</Superscript> tool provides comfortable means for switching between different levels of granularity.</Pgraph><Pgraph>To strategically <Mark2>monitor</Mark2> an information system means to continuously audit its quality. An important part is the quality assessment of the information system&#8217;s architecture. Therefore, quantitative architectural quality criteria are helpful. On the basis of relevant architectural components of a HIS, as defined by 3LGM<Superscript>2</Superscript>, the following quality criteria have been defined: functional redundancy <TextLink reference="19"></TextLink>, data redundancy, data availability <TextLink reference="20"></TextLink>, functional under-saturation, functional correspondence, informational redundancy, degree of heterogeneity and degree of computer-support. These quality criteria were implemented as part of the 3LGM<Superscript>2</Superscript> tool. Moreover the before mentioned reference-model supports systematically comparing information systems of different institutions <TextLink reference="21"></TextLink>.</Pgraph><SubHeadline>4.2 The 3LGM<Superscript>2</Superscript> for tactical information management</SubHeadline><Pgraph>Tactical information management deals with certain hospital functions. It aims to construct or to maintain components of the information system. Related activities are usually executed as projects. </Pgraph><Pgraph>Tactical projects usually start with a systems analysis of the organizational unit in which a new component shall be introduced. Again a continuously maintained 3LGM<Superscript>2</Superscript> model will provide easily with the current state of the IT-infrastructure in the unit and the institution as a whole. An analysis of the domain layer can identify those hospital functions and tasks of employees, which should be supported better in the future. Thus the domain layer will help structuring a document for the specification of new Soft- and Hardware to be selected at the market place. </Pgraph><Pgraph>Introducing a new information system&#8217;s component in a health care institution needs considerations on how to integrate it with the already existing components of the institution&#8217;s information system as well as with the components of the related tHIS. </Pgraph><Pgraph>Especially communication interfaces and links have to be planned and specified. Using a 3LGM<Superscript>2</Superscript> model of the current state of the HIS or tHIS and the 3LGM<Superscript>2</Superscript> tool the planned communication interfaces and links and the entire information system&#8217;s architecture can be constructed and planned similarly like using a computer aided design (CAD) tool for engineering. To support this task the 3LGM<Superscript>2</Superscript> tool provides e.g. reference models as templates for modeling HL7 messages and integration by means of communication servers. </Pgraph><Pgraph>Many projects will deal with problems, which are not unique for a particular institution. For example problems of archiving patient records digitally are common for hospitals on the way to an electronic patient record <TextLink reference="22"></TextLink>. In <TextLink reference="9"></TextLink> we reported on how to model archiving of patient records in hospitals by means of 3LGM<Superscript>2</Superscript>. Moreover we prepared a reference model for integrating medical record archiving systems <TextLink reference="23"></TextLink> into a hospital information system based on a guideline <TextLink reference="24"></TextLink>. Another reference model provides with a modelling template for transinstitutional communication standards, interfaces and links <TextLink reference="25"></TextLink>.</Pgraph><SubHeadline>4.3 The 3LGM<Superscript>2</Superscript> for operational information management</SubHeadline><Pgraph>Operational information management is responsible for maintaining the installed hospital information system and its components and will provide an adequate IT service <TextLink reference="26"></TextLink>. For this service a configuration management database is essential <TextLink reference="27"></TextLink>. The 3LGM<Superscript>2</Superscript> model of HIS or tHIS can serve as configuration management database. Using the 3LGM<Superscript>2</Superscript> tool and its analyzing functions employees at the service desk can easily find out, what physical data processing components may be the reason if a user reports problems concerning a particular application component e.g. the laboratory information system. Conversely, if a certain server breaks down, those hospital functions can be determined which may be affected.</Pgraph></TextBlock>
    <TextBlock linked="yes" name="5 Conclusion">
      <MainHeadline>5 Conclusion</MainHeadline><Pgraph>In the previous sections 3LGM<Superscript>2</Superscript> and the corresponding 3LGM<Superscript>2</Superscript> tool for modeling information systems was shortly introduced and possible opportunities for information management in a HIS as well as tHIS were illustrated. There are methods and tools comparable to our approach as has been discussed earlier in <TextLink reference="8"></TextLink> and <TextLink reference="9"></TextLink>. Newer approaches dealing with a thorough support of information systems&#8217; management can be found in the field of application portfolio management <TextLink reference="28"></TextLink>, <TextLink reference="29"></TextLink>, <TextLink reference="30"></TextLink>. Future work has to carefully look for an integration of 3LGM<Superscript>2</Superscript> and those methods and tools. </Pgraph><Pgraph>There are some organizational prerequisites for a useful application of 3LGM<Superscript>2</Superscript> in regional and even national settings. Especially for a tHIS, there must be a super-ordinate institution responsible for information management from a regional perspective. This might become an important challenge because healthcare regions, at least in Germany, are not necessarily institutional bodies with their own administration, but a rather loose coupling of autonomous institutions <TextLink reference="31"></TextLink>. Nevertheless, the super-ordinate institution could be a ministry for health, another health care body or even a health care enterprise. </Pgraph><Pgraph>So we finally can conclude that 3LGM<Superscript>2</Superscript> as modeling instrument for information systems can support information management in every setting where an information management authority is installed.</Pgraph></TextBlock>
    <TextBlock linked="yes" name="6 Acknowledgments">
      <MainHeadline>6 Acknowledgments</MainHeadline><Pgraph>This work is a result of the research project &#8220;Integrative modeling of structures and processes in hospital information systems&#8221; supported by the Deutsche Forschungsgemeinschaft (DFG), grant no. WI 1605&#47;2-1. </Pgraph></TextBlock>
    <TextBlock linked="yes" name="Notes">
      <MainHeadline>Notes</MainHeadline><SubHeadline>Competing interests</SubHeadline><Pgraph>The author declares that he has no competing interests.</Pgraph></TextBlock>
    <References linked="yes">
      <Reference refNo="1">
        <RefAuthor>Gulliford M</RefAuthor>
        <RefAuthor>Naithani S</RefAuthor>
        <RefAuthor>Morgan M</RefAuthor>
        <RefTitle>What is &#39;continuity of care&#39;&#63;</RefTitle>
        <RefYear>2006</RefYear>
        <RefJournal>J Health Serv Res Policy</RefJournal>
        <RefPage>248-50</RefPage>
        <RefTotal>Gulliford M, Naithani S, Morgan M. What is &#39;continuity of care&#39;&#63; J Health Serv Res Policy. 2006 Oct;11(4):248-50. DOI: 10.1258&#47;135581906778476490</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1258&#47;135581906778476490</RefLink>
      </Reference>
      <Reference refNo="2">
        <RefAuthor>Winter A</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2004</RefYear>
        <RefBookTitle>Health Information Systems. Yearbook of Medical Informatics</RefBookTitle>
        <RefPage>503-4</RefPage>
        <RefTotal>Winter A. Health Information Systems.  Yearbook of Medical Informatics. Stuttgart: Schattauer; 2004. p. 503-4.</RefTotal>
      </Reference>
      <Reference refNo="3">
        <RefAuthor>Haux R</RefAuthor>
        <RefAuthor>Winter A</RefAuthor>
        <RefAuthor>Ammenwerth E</RefAuthor>
        <RefAuthor>Brigl B</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2004</RefYear>
        <RefBookTitle>Strategic Information Management in Hospitals</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Haux R, Winter A, Ammenwerth E, Brigl B. Strategic Information Management in Hospitals. New York: Springer; 2004.</RefTotal>
      </Reference>
      <Reference refNo="4">
        <RefAuthor>Berg M</RefAuthor>
        <RefTitle>Patient care information systems and health care work: A sociotechnical approach</RefTitle>
        <RefYear>1999</RefYear>
        <RefJournal>Int J Med Inform</RefJournal>
        <RefPage>87-101</RefPage>
        <RefTotal>Berg M. Patient care information systems and health care work: A sociotechnical approach. Int J Med Inform. 1999;55(2):87-101. DOI: 10.1016&#47;S1386-5056(99)00011-8</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1016&#47;S1386-5056(99)00011-8</RefLink>
      </Reference>
      <Reference refNo="5">
        <RefAuthor>Haux R</RefAuthor>
        <RefTitle>Individualization, globalization and health - about sustainable information technologies and the aim of medical informatics</RefTitle>
        <RefYear>2006</RefYear>
        <RefJournal>Int J Med Inform</RefJournal>
        <RefPage>795-808</RefPage>
        <RefTotal>Haux R. Individualization, globalization and health - about sustainable information technologies and the aim of medical informatics. Int J Med Inform. 2006 Dec;75(12):795-808. DOI: 10.1016&#47;j.ijmedinf.2006.05.045</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1016&#47;j.ijmedinf.2006.05.045</RefLink>
      </Reference>
      <Reference refNo="6">
        <RefAuthor>Martin J</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>1990</RefYear>
        <RefBookTitle>Information Engineering, Book II: Planning &#38; Analysis</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Martin J. Information Engineering, Book II: Planning &#38; Analysis. Englewood Cliffs: Prentice Hall; 1990.</RefTotal>
      </Reference>
      <Reference refNo="7">
        <RefAuthor>Spewak SH</RefAuthor>
        <RefAuthor>Hill SC</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>1992</RefYear>
        <RefBookTitle>Enterprise Architecture Planning: Developing a blueprint for Data, Applications and Technology</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Spewak SH, Hill SC. Enterprise Architecture Planning: Developing a blueprint for Data, Applications and Technology. New York: John Wiley &#38; Sons; 1992.</RefTotal>
      </Reference>
      <Reference refNo="8">
        <RefAuthor>Winter A</RefAuthor>
        <RefAuthor>Brigl B</RefAuthor>
        <RefAuthor>Wendt T</RefAuthor>
        <RefTitle>Modeling Hospital Information Systems (Part 1): The Revised Three-Layer Graph-Based Meta Model 3LGM2</RefTitle>
        <RefYear>2003</RefYear>
        <RefJournal>Methods Inf Med</RefJournal>
        <RefPage>544-51</RefPage>
        <RefTotal>Winter A, Brigl B, Wendt T. Modeling Hospital Information Systems (Part 1): The Revised Three-Layer Graph-Based Meta Model 3LGM2. Methods Inf Med. 2003;42(5):544-51. DOI: 10.1267&#47;METH03050544</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1267&#47;METH03050544</RefLink>
      </Reference>
      <Reference refNo="9">
        <RefAuthor>Wendt T</RefAuthor>
        <RefAuthor>H&#228;ber A</RefAuthor>
        <RefAuthor>Brigl B</RefAuthor>
        <RefAuthor>Winter A</RefAuthor>
        <RefTitle>Modeling Hospital Information Systems (Part 2): Using the 3LGM2 Tool for Modeling Patient Record Management</RefTitle>
        <RefYear>2004</RefYear>
        <RefJournal>Methods Inf Med</RefJournal>
        <RefPage>256-67</RefPage>
        <RefTotal>Wendt T, H&#228;ber A, Brigl B, Winter A. Modeling Hospital Information Systems (Part 2): Using the 3LGM2 Tool for Modeling Patient Record Management. Methods Inf Med. 2004;43(3):256-67. DOI: 10.1267&#47;METH04030256</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1267&#47;METH04030256</RefLink>
      </Reference>
      <Reference refNo="10">
        <RefAuthor>Brigl B</RefAuthor>
        <RefAuthor>Ammenwerth E</RefAuthor>
        <RefAuthor>Dujat C</RefAuthor>
        <RefAuthor>Graber S</RefAuthor>
        <RefAuthor>Gro&#91;ss&#93;e A</RefAuthor>
        <RefAuthor>Haber A</RefAuthor>
        <RefAuthor></RefAuthor>
        <RefTitle>Preparing strategic information management plans for hospitals: a practical guideline:  SIM plans for hospitals: a guideline</RefTitle>
        <RefYear>2005</RefYear>
        <RefJournal>Int J Med Inform</RefJournal>
        <RefPage>51-65</RefPage>
        <RefTotal>Brigl B, Ammenwerth E, Dujat C, Graber S, Gro&#91;ss&#93;e A, Haber A, et al. Preparing strategic information management plans for hospitals: a practical guideline:  SIM plans for hospitals: a guideline. Int J Med Inform. 2005 2005&#47;1;74(1):51-65. DOI: 10.1016&#47;j.ijmedinf.2004.09.002</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1016&#47;j.ijmedinf.2004.09.002</RefLink>
      </Reference>
      <Reference refNo="11">
        <RefAuthor>Seidel C</RefAuthor>
        <RefAuthor>Lowes D</RefAuthor>
        <RefAuthor>Haux R</RefAuthor>
        <RefTitle>IT-Strategie des Klinikums Braunschweig</RefTitle>
        <RefYear>2006</RefYear>
        <RefJournal>Forum der Medizinischen Dokumentation und Medizinischen Informatik</RefJournal>
        <RefPage>100-5</RefPage>
        <RefTotal>Seidel C, Lowes D, Haux R. IT-Strategie des Klinikums Braunschweig. Forum der Medizinischen Dokumentation und Medizinischen Informatik. 2006;8(3):100-5.</RefTotal>
      </Reference>
      <Reference refNo="12">
        <RefAuthor>Gr&#228;ber S</RefAuthor>
        <RefAuthor>Geib D</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2000</RefYear>
        <RefBookTitle>Rahmenkonzept f&#252;r das Klinikinformationssystem der Universit&#228;tskliniken des Saarlandes (1. Fortschreibung)</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Gr&#228;ber S, Geib D. Rahmenkonzept f&#252;r das Klinikinformationssystem der Universit&#228;tskliniken des Saarlandes (1. Fortschreibung). Homburg: Universit&#228;tskliniken des Saarlandes: Bereich Klinische Informationsverarbeitung; 2000.</RefTotal>
      </Reference>
      <Reference refNo="13">
        <RefAuthor>Haux R</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>1997</RefYear>
        <RefBookTitle>Informationsverarbeitung im Klinikum der Universit&#228;t Heidelberg: Rahmenkonzept f&#252;r das Heidelberger Klinikuminformationssystem 1997 bis 2002</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Haux R, ed. Informationsverarbeitung im Klinikum der Universit&#228;t Heidelberg: Rahmenkonzept f&#252;r das Heidelberger Klinikuminformationssystem 1997 bis 2002. Heidelberg: Klinikum der Universit&#228;t Heidelberg; 1997.</RefTotal>
      </Reference>
      <Reference refNo="14">
        <RefAuthor>Winter A</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2005</RefYear>
        <RefBookTitle>Rahmenkonzept f&#252;r die Weiterentwicklung des Informationssystems des Universit&#228;tsklinikums Leipzig A&#246;R 2005-2007</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Winter A, ed. Rahmenkonzept f&#252;r die Weiterentwicklung des Informationssystems des Universit&#228;tsklinikums Leipzig A&#246;R 2005-2007. Leipzig: Universit&#228;tsklinikum Leipzig A&#246;R; 2005.</RefTotal>
      </Reference>
      <Reference refNo="15">
        <RefAuthor>Fettke P</RefAuthor>
        <RefAuthor>Loos P</RefAuthor>
        <RefTitle>Referenzmodellierungsforschung</RefTitle>
        <RefYear>2004</RefYear>
        <RefJournal>Wirtschaftsinformatik</RefJournal>
        <RefPage>331-40</RefPage>
        <RefTotal>Fettke P, Loos P. Referenzmodellierungsforschung. Wirtschaftsinformatik. 2004;46:331-40.</RefTotal>
      </Reference>
      <Reference refNo="16">
        <RefAuthor>H&#252;bner-Bloder G</RefAuthor>
        <RefAuthor>Ammenwerth E</RefAuthor>
        <RefAuthor>Brigl B</RefAuthor>
        <RefAuthor>Winter A</RefAuthor>
        <RefTitle>Specification of a reference model for the domain layer of a hospital information system</RefTitle>
        <RefYear>2005</RefYear>
        <RefJournal>Stud Health Technol Inform</RefJournal>
        <RefPage>497-502</RefPage>
        <RefTotal>H&#252;bner-Bloder G, Ammenwerth E, Brigl B, Winter A. Specification of a reference model for the domain layer of a hospital information system. Stud Health Technol Inform. 2005;116:497-502.</RefTotal>
      </Reference>
      <Reference refNo="17">
        <RefAuthor>Winter A</RefAuthor>
        <RefAuthor>Brigl B</RefAuthor>
        <RefAuthor>Heller O</RefAuthor>
        <RefAuthor>Mueller U</RefAuthor>
        <RefAuthor>Struebing A</RefAuthor>
        <RefAuthor>Wendt T</RefAuthor>
        <RefTitle>Supporting Information Management for Regional Health Information Systems by Models with Communication Path Analysis</RefTitle>
        <RefYear>2005</RefYear>
        <RefBookTitle>Proceedings IDEAS Workshop on Medical Information Systems: The Digital Hospital (Beijing 2004)</RefBookTitle>
        <RefPage>139-46</RefPage>
        <RefTotal>Winter A, Brigl B, Heller O, Mueller U, Struebing A, Wendt T. Supporting Information Management for Regional Health Information Systems by Models with Communication Path Analysis. In: Desai BC, Rao K, Li B, Zhang F, eds. Proceedings IDEAS Workshop on Medical Information Systems: The Digital Hospital (Beijing 2004). Los Alamitos: IEEE Computer Society; 2005. p. 139-46.</RefTotal>
      </Reference>
      <Reference refNo="18">
        <RefAuthor>Anonym</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2003</RefYear>
        <RefBookTitle>Saxonian Ministry for Social Affairs</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Saxonian Ministry for Social Affairs. Saxtelemed. 2003 &#91;updated 2003; cited&#93;. Available from: http:&#47;&#47;www.saxtelemed.de</RefTotal>
        <RefLink>http:&#47;&#47;www.saxtelemed.de</RefLink>
      </Reference>
      <Reference refNo="19">
        <RefAuthor>Winter A</RefAuthor>
        <RefAuthor>Str&#252;bing A</RefAuthor>
        <RefAuthor>Brigl B</RefAuthor>
        <RefAuthor>Haux R</RefAuthor>
        <RefAuthor>I&#223;ler L</RefAuthor>
        <RefTitle>Ontology-Based Assessment of Functional Redundancy in Health Information Systems</RefTitle>
        <RefYear>2009</RefYear>
        <RefJournal>Lecture Notes in Computer Science (LNCS)</RefJournal>
        <RefPage>213-26</RefPage>
        <RefTotal>Winter A, Str&#252;bing A, Brigl B, Haux R, I&#223;ler L. Ontology-Based Assessment of Functional Redundancy in Health Information Systems. Lecture Notes in Computer Science (LNCS). 2009;5421:213-26.</RefTotal>
      </Reference>
      <Reference refNo="20">
        <RefAuthor>Winter A</RefAuthor>
        <RefAuthor>Str&#252;bing A</RefAuthor>
        <RefTitle>Model-Based Assessment of Data Availability in Health Information Systems</RefTitle>
        <RefYear>2008</RefYear>
        <RefJournal>Methods Inf Med</RefJournal>
        <RefPage>417-24</RefPage>
        <RefTotal>Winter A, Str&#252;bing A. Model-Based Assessment of Data Availability in Health Information Systems. Methods Inf Med. 2008;47(5):417-24. DOI: 10.3414&#47;ME9123</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.3414&#47;ME9123</RefLink>
      </Reference>
      <Reference refNo="21">
        <RefAuthor>Jahn F</RefAuthor>
        <RefAuthor>Issler L</RefAuthor>
        <RefAuthor>Winter A</RefAuthor>
        <RefAuthor>Takabayashi K</RefAuthor>
        <RefTitle>Comparing a Japanese and a German hospital information system</RefTitle>
        <RefYear>2009</RefYear>
        <RefJournal>Methods Inf Med</RefJournal>
        <RefPage>531-9</RefPage>
        <RefTotal>Jahn F, Issler L, Winter A, Takabayashi K. Comparing a Japanese and a German hospital information system. Methods Inf Med. 2009;48(6):531-9. DOI: 10.3414&#47;ME09-01-0023</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.3414&#47;ME09-01-0023</RefLink>
      </Reference>
      <Reference refNo="22">
        <RefAuthor>Hollerbach A</RefAuthor>
        <RefAuthor>Brandner R</RefAuthor>
        <RefAuthor>Bess A</RefAuthor>
        <RefAuthor>Schmucker R</RefAuthor>
        <RefAuthor>Bergh B</RefAuthor>
        <RefTitle>Electronically signed documents in health care-analysis and assessment of data formats and transformation</RefTitle>
        <RefYear>2005</RefYear>
        <RefJournal>Methods Inf Med</RefJournal>
        <RefPage>520-7</RefPage>
        <RefTotal>Hollerbach A, Brandner R, Bess A, Schmucker R, Bergh B. Electronically signed documents in health care-analysis and assessment of data formats and transformation. Methods Inf Med. 2005;44(4):520-7.</RefTotal>
      </Reference>
      <Reference refNo="23">
        <RefAuthor>Lehmann S</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2006</RefYear>
        <RefBookTitle>3LGM&#178;-basiertes Referenzmodell f&#252;r die digitale Archivierung von Patientenunterlagen</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Lehmann S. 3LGM&#178;-basiertes Referenzmodell f&#252;r die digitale Archivierung von Patientenunterlagen &#91;Diploma-Thesis&#93;. Leipzig (Germany): University of Leipzig; 2006.</RefTotal>
      </Reference>
      <Reference refNo="24">
        <RefAuthor>H&#228;ber A</RefAuthor>
        <RefAuthor>Dujat C</RefAuthor>
        <RefAuthor>Schm&#252;cker P</RefAuthor>
        <RefAuthor>Be&#223; A</RefAuthor>
        <RefAuthor>Erdmann J</RefAuthor>
        <RefAuthor>Herrmann A</RefAuthor>
        <RefAuthor>.</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2005</RefYear>
        <RefBookTitle>Leitfaden f&#252;r das rechnerunterst&#252;tzte Dokumentenmanagement und die digitale Archivierung von Patientenunterlagen im Gesunheitswesen - Empfehlungen der Arbeitsgruppe &#34;Archivierung von Krankenunterlagen&#34; der Deutschen Gesellschaft f&#252;r Medizinische Informatik, Biometrie und Epidemiologie</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>H&#228;ber A, Dujat C, Schm&#252;cker P, Be&#223; A, Erdmann J, Herrmann A, et al., eds. Leitfaden f&#252;r das rechnerunterst&#252;tzte Dokumentenmanagement und die digitale Archivierung von Patientenunterlagen im Gesunheitswesen - Empfehlungen der Arbeitsgruppe &#34;Archivierung von Krankenunterlagen&#34; der Deutschen Gesellschaft f&#252;r Medizinische Informatik, Biometrie und Epidemiologie. Darmstadt: GIT VERLAG; 2005.</RefTotal>
      </Reference>
      <Reference refNo="25">
        <RefAuthor>St&#228;ubert S</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2005</RefYear>
        <RefBookTitle>Referenzmodell f&#252;r die Kommunikation eines Universit&#228;tsklinikums mit dem niedergelassenen Bereich</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>St&#228;ubert S. Referenzmodell f&#252;r die Kommunikation eines Universit&#228;tsklinikums mit dem niedergelassenen Bereich &#91;Diploma-Thesis&#93;. Leipzig (Germany): University of Leipzig; 2005.</RefTotal>
      </Reference>
      <Reference refNo="26">
        <RefAuthor>Office of Government Commerce (OGC)</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2007</RefYear>
        <RefBookTitle>Service Design</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Office of Government Commerce (OGC). Service Design. London: TSO; 2007.</RefTotal>
      </Reference>
      <Reference refNo="27">
        <RefAuthor>Macfarlane I</RefAuthor>
        <RefAuthor>Rudd C</RefAuthor>
        <RefTitle></RefTitle>
        <RefYear>2003</RefYear>
        <RefBookTitle>IT Service Management Version 2.1.b</RefBookTitle>
        <RefPage></RefPage>
        <RefTotal>Macfarlane I, Rudd C. IT Service Management Version 2.1.b. Reading: itSMF Ltd.; 2003.</RefTotal>
      </Reference>
      <Reference refNo="28">
        <RefAuthor>Foorthuis R</RefAuthor>
        <RefAuthor>Hofman F</RefAuthor>
        <RefAuthor>Brinkkemper S</RefAuthor>
        <RefAuthor>Bos R</RefAuthor>
        <RefTitle>Assessing Business and IT Projects on Compliance with Enterprise Architecture</RefTitle>
        <RefYear>2009</RefYear>
        <RefTotal>Foorthuis R, Hofman F, Brinkkemper S, Bos R. Assessing Business and IT Projects on Compliance with Enterprise Architecture.  Proceedings of GRCIS 2009 - CAISE Workshop on Governance, Risk and Compliance of Information Systems; 2009. 2009.</RefTotal>
      </Reference>
      <Reference refNo="29">
        <RefAuthor>Riempp G</RefAuthor>
        <RefAuthor>Gieffers-Ankel S</RefAuthor>
        <RefTitle>Application portfolio management: a decision-oriented view of enterprise architecture</RefTitle>
        <RefYear>2007</RefYear>
        <RefJournal>Information Systems and E-Business Management</RefJournal>
        <RefPage>359-78</RefPage>
        <RefTotal>Riempp G, Gieffers-Ankel S. Application portfolio management: a decision-oriented view of enterprise architecture. Information Systems and E-Business Management. 2007;5(4):359-78. DOI: 10.1007&#47;s10257-007-0052-2</RefTotal>
        <RefLink>http:&#47;&#47;dx.doi.org&#47;10.1007&#47;s10257-007-0052-2</RefLink>
      </Reference>
      <Reference refNo="30">
        <RefAuthor>Simon D</RefAuthor>
        <RefAuthor>Fischbach K</RefAuthor>
        <RefAuthor>Schoder D</RefAuthor>
        <RefTitle>Application Portfolio Management-An Integrated Framework and a Software Tool Evaluation Approach</RefTitle>
        <RefYear>2010</RefYear>
        <RefJournal>Communications of the Association for Information Systems</RefJournal>
        <RefPage>Article 3</RefPage>
        <RefTotal>Simon D, Fischbach K, Schoder D. Application Portfolio Management-An Integrated Framework and a Software Tool Evaluation Approach. Communications of the Association for Information Systems. 2010;26(1):Article 3.</RefTotal>
      </Reference>
      <Reference refNo="31">
        <RefAuthor>Hellrung N</RefAuthor>
        <RefAuthor>Gusew N</RefAuthor>
        <RefAuthor>Willkomm M</RefAuthor>
        <RefAuthor>Haux R</RefAuthor>
        <RefTitle>IT-based information management in health care networks: the MedoCom approach</RefTitle>
        <RefYear>2008</RefYear>
        <RefJournal>Stud Health Technol Inform</RefJournal>
        <RefPage>623-8</RefPage>
        <RefTotal>Hellrung N, Gusew N, Willkomm M, Haux R. IT-based information management in health care networks: the MedoCom approach. Stud Health Technol Inform. 2008;136:623-8.</RefTotal>
      </Reference>
    </References>
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          <Caption><Pgraph><Mark1>Figure 2: The 3LGM</Mark1><Mark1><Superscript>2</Superscript></Mark1><Mark1> tool: modeling canvas offering typical operations for graphical display and  modeling (right), a model browser for hierarchical browsing through the model structure (left), a menu bar and tool bars for accessing common operations (top) (for more details please refer to &#91;9&#93; and http:&#47;&#47;www.3lgm2.de&#47;).</Mark1></Pgraph></Caption>
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          <Caption><Pgraph><Mark1>Figure 3:  3LGM&#178; model of the Saxonian tHIS:  Cutout of the overview at the logical tool layer</Mark1></Pgraph></Caption>
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