Single-stage multilamellar upper eyelid reconstruction after traumatic avulsion injury from a dog bite

iprs000198 10.3205/iprs000198 urn:nbn:de:0183-iprs0001987 Case Report Single-stage multilamellar upper eyelid reconstruction after traumatic avulsion injury from a dog bite Einzeitige multilamelläre Rekonstruktion des Oberlids nach traumatischer Avulsionsverletzung durch Hundebiss Ribeiro Cavadas Ribeiro Cavadas Bernardo B MD

Plastic Surgery Department and Burn Unit, Unidade Local de Saúde de São José, Rua José António Serrano, 1150-199 Lisbon, Portugal, Phone: +351919844949Plastic Surgery Department and Burn Unit, Unidade Local de Saúde de São José, Lisbon, Portugal

bernardoribeirocavadas@gmail.com author Oliveira Pires Oliveira Pires Inês I MD

Plastic Surgery Department and Burn Unit, Unidade Local de Saúde de São José, Lisbon, Portugal

ipires@campus.ul.pt author Alves Alves Sara S MD

Pathology Department, Unidade Local de Saúde de São José, Lisbon, Portugal Anatomy Department, NOVA Medical School, Lisbon, Portugal

saraalves79@hotmail.com author Magriço Magriço Ana Maria AM MD

Ophthalmology Department, Unidade Local de Saúde de São José, Lisbon, Portugal

ana.magrico@ulssjose.min-saude.pt author Pais Pais Diogo D PhD

Anatomy Department, NOVA Medical School, Lisbon, Portugal

diogo.pais@nms.unl.pt author Casal Casal Diogo D PhD

Plastic Surgery Department and Burn Unit, Unidade Local de Saúde de São José, Lisbon, Portugal Anatomy Department, NOVA Medical School, Lisbon, Portugal

diogo.bogalhao80@gmail.com author German Medical Science GMS Publishing House

Düsseldorf

610 26780-50-7 Polyglactin 910 56-75-7 Chloramphenicol eyelids reconstructive surgical procedures bites and stings surgical flaps traumatic amputation 20261014 engl This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). 2193-8091 15 GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW GMS Interdiscip Plast Reconstr Surg DGPW 05 Ziel: Vorstellung eines seltenen Falls einer vollständigen multilamellären Avulsion des Oberlids nach einem Hundebiss, die erfolgreich durch eine einzeitige Rekonstruktion behandelt wurde. Methoden: Nach sorgfältigem Debridement erfolgte die einzeitige Rekonstruktion mit einem lateralen myokutanen V-Y-Verschiebelappen, Lappen des M. levator palpebrae superioris und M. tarsalis superior (Müller-Muskel) sowie einem aus dem amputierten Gewebe präparierten tarsokonjunktivalen Haut-Komposit-Transplantat. Ergebnisse: Fünf Jahre postoperativ zeigte die Patientin exzellente funktionelle und ästhetische Ergebnisse, einschließlich vollständiger Lidmobilität, normalem Schutz der Augenoberfläche und symmetrischer Lidkontur ohne Retraktion, Ektropium oder Entropium. Schlussfolgerungen: Eine sorgfältige einzeitige multilamelläre Rekonstruktion einschließlich der Wiederverwendung von avulsiertem Gewebe nach Debridement kann bei kontaminiertem Trauma die entscheidende Lidfunktion und Ästhetik wiederherstellen und so zweizeitige Eingriffe und Hebemorbidität vermeiden. Objective: To report a rare case of complete multilamellar avulsion of the upper eyelid following a dog bite, successfully managed with a single-stage reconstruction. Methods: After meticulous debridement, single-stage reconstruction w</PlainText></TextGroup>as performed using a lateral V-Y myocutaneous advancement flap, superior levator palpebrae superioris and Müller’s muscle flaps, and a composite tarsoconjunctival-skin graft prepared from the amputated tissue. </Pgraph><Pgraph><Mark1>Results:</Mark1> At five years postoperatively, the patient demonstrated excellent functional and aesthetic outcomes, including full eyelid mobility, normal ocular surface protection, and symmetric eyelid contour without retraction, ectropion, or entropion.</Pgraph><Pgraph><Mark1>Conclusions:</Mark1> Meticulous single-stage multilamellar reconstruction, including reuse of avulsed tissue after debridement, can restore critical eyelid function and aesthetics in contaminated trauma, avoiding staged procedures and donor site morbidity.</Pgraph></Abstract> <TextBlock name="Introduction" linked="yes"> <MainHeadline>Introduction</MainHeadline><Pgraph>The eyelids are complex, dynamic structures essential for protecting the eye and preserving vision <TextLink reference="1"></TextLink>, <TextLink reference="2"></TextLink>. The upper eyelid plays a crucial role in corneal protection and ocular surface lubrication <TextLink reference="3"></TextLink>. Traumatic eyelid avulsion with full-thickness loss of all three lamellae is extremely rare and represents a significant reconstructive challenge <TextLink reference="4"></TextLink>, <TextLink reference="5"></TextLink>. Dog bites are a common cause of facial trauma, but complete multilamellar eyelid avulsion is particularly infrequent and raises concerns regarding contamination and tissue viability <TextLink reference="6"></TextLink>. Traditionally, large full-thickness eyelid defects require staged procedures such as the Cutler-Beard flap, which carry donor site morbidity and potential functional limitations <TextLink reference="7"></TextLink>, <TextLink reference="8"></TextLink>. Ideally, amputated segments should be replanted using microvascular anastomoses; however, eyelid vessels are extremely small, and documented cases of successful replantation are extremely rare <TextLink reference="9"></TextLink>. We present a rare case of complete multilamellar avulsion of the upper eyelid following a dog bite, successfully managed with a single-stage reconstruction using local flaps and a composite graft from the avulsed tissue.</Pgraph></TextBlock> <TextBlock name="Case description" linked="yes"> <MainHeadline>Case description</MainHeadline><Pgraph>A 20-year-old female with no prior medical conditions, allergies, or immunosuppression, and up-to-date vaccinations, presented to the emergency department following a dog bite to the right upper eyelid. The injury resulted in complete avulsion of the middle two-thirds of the upper eyelid involving all three lamellae. The amputated tissue was brought in and preserved under appropriate conditions in saline-soaked gauze. Ophthalmologic assessment excluded acute ocular injuries, and the globe remained intact (Figure 1 <ImgLink imgNo="1" imgType="figure" /> and Figure 2 <ImgLink imgNo="2" imgType="figure" />).</Pgraph><Pgraph>The patient was taken to the operating room within <TextGroup><PlainText>6 h</PlainText></TextGroup>ours of the trauma. Under general anesthesia, meticulous wound irrigation and debridement were performed to reduce the risk of infection. After thorough examination of the avulsed segment under the operating microscope, no vessels suitable for microvascular anastomoses were found. Devitalized edges of the amputated tissue were carefully trimmed. To facilitate reconstruction, the avulsed eyelid segment was incised in three layers along the margin, as shown in Figure 3 <ImgLink imgNo="3" imgType="figure" />: the anterior layer (skin and subcutaneous tissue), the middle layer (orbicularis muscle), and the posterior layer (tarsal plate and palpebral conjunctiva).</Pgraph><Pgraph>Initially, a superior lateral canthotomy was performed to allow mobilization of the lateral aspect of the remaining eyelid. A lateral V-Y myocutaneous advancement flap was mobilized medially, with the orbicularis muscle of this flap positioned between the subcutaneous tissue and orbicularis muscle of the amputated segment. The superior levator palpebrae superioris and Müller's muscle from the upper margin of the wound were mobilized inferiorly and sutured into the gap between the orbicularis muscle and the tarsal plate/conjunctiva of the avulsed eyelid.</Pgraph><Pgraph>The free margins of the bulbar and palpebral conjunctiva were sutured together with an inverted running 7/0 polyglactin 910 suture (Vicryl, Ethicon Inc., CAS: 26780-50-7). The flaps and composite graft were carefully inset to restore eyelid height, contour, and lamellar integrity, ensuring functional closure and ocular surface protection. The flaps were secured with interrupted 6/0 polyglactin 910 sutures (Figure 4 <ImgLink imgNo="4" imgType="figure" />).</Pgraph><Pgraph>Postoperatively, the eyelid was dressed for 3 days with chloramphenicol eye ointment (CAS: 56-75-7) and petroleum jelly gauze. The wounds were exposed on postoperative day 4, irrigated with sterile saline, and treated with topical ointment three times daily for 15 days. The patient was discharged on postoperative day 8 with unremarkable recovery. </Pgraph><Pgraph>The composite graft showed good integration, and surgical wounds healed appropriately. At five years postoperatively, the patient maintained excellent eyelid mobility with full opening and closing, normal ocular surface protection without lagophthalmos, and no episodes of keratitis or ocular complications. The reconstructed eyelid preserved adequate contour and symmetry, with an inconspicuous scar (Figure 5 <ImgLink imgNo="5" imgType="figure" />).</Pgraph></TextBlock> <TextBlock name="Discussion" linked="yes"> <MainHeadline>Discussion</MainHeadline><Pgraph>Traumatic avulsion of the upper eyelid with full-thickness loss of all three lamellae represents one of the most challenging oculoplastic reconstructive problems <TextLink reference="4"></TextLink>, <TextLink reference="5"></TextLink>. The presence of contamination from a dog bite adds significant concern regarding tissue viability and infection risk <TextLink reference="6"></TextLink>.</Pgraph><Pgraph>Traditionally, for large full-thickness upper eyelid defects, reconstructive options depend on defect size and extent. Direct primary closure is feasible only for small defects. Larger defects typically require local flaps, skin grafts, or combined techniques. For extensive defects involving all lamellae, staged procedures such as the Cutler-Beard flap have historically been the standard approach, though these require a second stage, carry donor site morbidity (particularly from the contralateral upper eyelid), and may result in functional limitations <TextLink reference="7"></TextLink>, <TextLink reference="8"></TextLink>. Alternative approaches include free tissue transfer or use of distant grafts; however, these do not provide optimal “like-for-like” replacement of eyelid tissue <TextLink reference="10"></TextLink>.</Pgraph><Pgraph>The key advantage of the single-stage approach used in this case was the ability to restore all three lamellae in one operation while preserving the physiologic and structural properties of native eyelid tissue. By meticulously debriding the avulsed segment, removing devitalized tissue, and preparing it as a composite graft – subdividing it into its constituent layers and inlaying them with appropriate vascularization from local flaps – we achieved functional multilayer restoration. This avoided donor site morbidity from contralateral tarsus, auricular cartilage, or hard palate grafts.</Pgraph><Pgraph>A critical point in this case was that despite the contaminated nature of the dog bite injury, meticulous debridement and preparation of the amputated tissue allowed for its safe and effective reuse. The long-term follow-up demonstrates the durability of this strategy, with the patient maintaining full eyelid mobility, adequate corneal protection, and aesthetic symmetry without retraction, ectropion, or entropion at five years. In this patient, the favorable outcome indicates that the reuse of avulsed tissue from a contaminated injury can be a successful strategy when combined with meticulous debridement and vascularized flap coverage, potentially offering an alternative to staged procedures in similar clinical scenarios.</Pgraph><Pgraph>Limitations of this approach include the following: </Pgraph><Pgraph><OrderedList><ListItem level="1" levelPosition="1" numString="1.">this is a single case report and does not provide comparative data to draw generalizable conclusions; </ListItem><ListItem level="1" levelPosition="2" numString="2.">the technique requires relatively well-preserved tissue suitable for composite grafting; </ListItem><ListItem level="1" levelPosition="3" numString="3.">success depends on early presentation and operative intervention; </ListItem><ListItem level="1" levelPosition="4" numString="4.">meticulous debridement and layering require expertise in oculoplastic surgery and microsurgical technique; and </ListItem><ListItem level="1" levelPosition="5" numString="5.">long-term follow-up data beyond this single case are needed to determine reproducibility and frequency of complications. </ListItem></OrderedList></Pgraph><Pgraph>Although technically straightforward, this surgical option requires further validation through case series or comparative studies from other authors and surgical centers.</Pgraph></TextBlock> <TextBlock name="Conclusion" linked="yes"> <MainHeadline>Conclusion</MainHeadline><Pgraph>This case demonstrates that single-stage multilamellar reconstruction using local flaps and a composite graft from avulsed tissue can achieve excellent outcomes. However, the success of this approach likely depends on factors such as early presentation, availability of relatively well-preserved tissue, and the use of vascularized local flaps.</Pgraph></TextBlock> <TextBlock name="Notes" linked="yes"> <MainHeadline>Notes</MainHeadline><SubHeadline>Ethics</SubHeadline><Pgraph>The patient provided written informed consent for the publication of this case report and accompanying images. This report adhered to the ethical principles outlined in the Declaration of Helsinki as amended in 2013.</Pgraph><SubHeadline>Competing interests</SubHeadline><Pgraph>The authors declare that they have no competing interests.</Pgraph></TextBlock> <References linked="yes"> <Reference refNo="1"> <RefAuthor>DiFrancesco LM</RefAuthor> <RefAuthor>Codner MA</RefAuthor> <RefAuthor>McCord CD</RefAuthor> <RefTitle>Upper eyelid reconstruction</RefTitle> <RefYear>2004</RefYear> <RefJournal>Plast Reconstr Surg</RefJournal> <RefPage>98e-107e</RefPage> <RefTotal>DiFrancesco LM, Codner MA, McCord CD. Upper eyelid reconstruction. Plast Reconstr Surg. 2004 Dec;114(7):98e-107e. 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DOI: 10.1016/j.ophtha.2013.10.010</RefTotal> <RefLink>https://doi.org/10.1016/j.ophtha.2013.10.010</RefLink> </Reference> </References> <Media> <Tables> <NoOfTables>0</NoOfTables> </Tables> <Figures> <Figure width="407" height="319" format="png"> <MediaNo>1</MediaNo> <MediaID>1</MediaID> <Caption><Pgraph><Mark1>Figure 1: Preoperative photograph showing complete avulsion of the middle two-thirds of the right upper eyelid following dog bite. The globe remains intact without acute injury. </Mark1></Pgraph></Caption> </Figure> <Figure width="650" height="363" format="png"> <MediaNo>2</MediaNo> <MediaID>2</MediaID> <Caption><Pgraph><Mark1>Figure 2: Intraoperative photograph of the amputated upper eyelid tissue immediately after receipt in the operating room. A ruler is included for scale reference. The tissue was preserved and used for composite graft reconstruction. </Mark1></Pgraph></Caption> </Figure> <Figure width="367" height="645" format="png"> <MediaNo>3</MediaNo> <MediaID>3</MediaID> <Caption><Pgraph><Mark1>Figure 3: Sagittal section of cadaveric upper eyelid stained with Masson’s trichrome, original magnification x10, demonstrating the trilayer anatomy. The anterior lamella includes skin (1), subcutaneous fat (2), and orbicularis oculi muscle (3). The middle lamella includes pre-septal fat (4), orbital septum (5), and post-septal fat pads (6). The posterior lamella comprises the tarsal plate (7) and palpebral conjunctiva (8). Upper eyelid specialized structures are visible: tarsal (meibomian) glands (9), sebaceous glands of eyelashes (Zeis glands) (10), apocrine glands (Moll glands) (11), and accessory lacrimal glands (Wolfring glands) (12). Eyelashes (black arrowheads), peripheral superior palpebral arterial arcade (yellow arrowhead), and marginal superior palpebral artery (asterisk) are noted. Red and blue dotted lines represent surgical incisions used to divide the amputated eyelid into layers for vascularization. </Mark1><LineBreak></LineBreak>An, anterior; S, superior. Scale bar = 1 mm. </Pgraph></Caption> </Figure> <Figure width="366" height="296" format="png"> <MediaNo>4</MediaNo> <MediaID>4</MediaID> <Caption><Pgraph><Mark1>Figure 4: Immediate postoperative photograph demonstrating reconstruction using V-Y myocutaneous advancement flap and composite graft inset. Sutures are visible at the reconstruction site showing multilayer restoration.</Mark1></Pgraph></Caption> </Figure> <Figure width="368" height="286" format="png"> <MediaNo>5</MediaNo> <MediaID>5</MediaID> <Caption><Pgraph><Mark1>Figure 5: Long-term follow-up photograph at five years postoperatively demonstrating excellent functional and aesthetic outcome with symmetric eyelid contour, full mobility, and inconspicuous scar. No retraction, lagophthalmos, ectropion, or entropion present.</Mark1></Pgraph></Caption> </Figure> <NoOfPictures>5</NoOfPictures> </Figures> <InlineFigures> <NoOfPictures>0</NoOfPictures> </InlineFigures> <Attachments> <NoOfAttachments>0</NoOfAttachments> </Attachments> </Media> </OrigData> </GmsArticle>