Isobornylacrylat
MAK-Begründung
Andrea Hartwig1 (Vorsitzende der Ständigen Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft)MAK Commission2
1 Institut für Angewandte Biowissenschaften, Abteilung Lebensmittelchemie und Toxikologie, Karlsruher Institut für Technologie (KIT), Adenauerring 20a, Geb. 50.41, 76131 Karlsruhe, Deutschland
2 Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Deutschland
Abstract
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated isobornyl acrylate [5888‐33‐5] considering its skin and respiratory sensitizing potential.
There are several cases of contact sensitization in humans and the results were clearly exposure‐related. A positive result in a local lymph node assay confirms that the substance is a skin sensitizer. Data for sensitization of the airways are not available. Isobornyl acrylate is designated with “Sh”.