Cover: The MAK Collection for Occupational Health and Safety

The MAK Collection for Occupational Health and Safety

German Research Foundation – Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area
(MAK Commission)

ISSN 2509-2383



Zirkonium und seine Verbindungen (außer Zirkoniumdioxid)

MAK-Begründung, Nachtrag

  Andrea Hartwig1 (Vorsitz der Ständigen Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft)
  MAK Commission2

1 Institut für Angewandte Biowissenschaften, Abteilung Lebensmittelchemie und Toxikologie, Karlsruher Institut für Technologie (KIT), Adenauerring 20a, Geb. 50.41, 76131 Karlsruhe, Deutschland
2 Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Deutschland

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the workplace (MAK value) for zirconium and its compounds. No new data are available that would be relevant for the derivation of a MAK value for zirconium compounds, with the exception of zirconium dioxide (see documentation “Zirconium dioxide”, to be published in 2019). Therefore, zirconium and its compounds (except zirconium dioxide) are listed in Section II b of the List of MAK and BAT Values. Based on the new human and animal data, zirconium and its compounds (except zirconium dioxide) are not regarded as sensitizers. Dermal absorption does not contribute to systemic toxicity.


Keywords

zirconium, zirconium compounds, MAK value, maximum workplace concentration, sensitization, toxicity